Browse by Authors

2024

Mohammadi, Somayeh and PourKarimi, Latif and Zschäbitz, Manuel and Aretz, Tristan and De Mecquenem, Ninon and Leser, Ulf and Reinert, Knut (2024) Optimizing Job/Task Granularity for Metagenomic Workflows in Heterogeneous Cluster Infrastructures. In: EDBT/ICDT 2024 Joint Conference: 8th International workshop on Data Analytics solutions for Real-LIfe APplications (DARLI-AP).

Hauswedell, Hannes and Hetzel, Sara and Gottlieb, Simon G and Kretzmer, Helene and Meissner, Alexander and Reinert, Knut and Cowen, Lenore (2024) Lambda3: homology search for protein, nucleotide, and bisulfite-converted sequences. Bioinformatics, 40 (3). ISSN 1367-4811

Pan, Chenxu and Reinert, Knut and Valencia, Alfonso (2024) A simple refined DNA minimizer operator enables 2-fold faster computation. Bioinformatics, 40 (2). ISSN 1367-4811

2023

Piro, Vitor C. and Reinert, Knut (2023) ganon2: up-to-date and scalable metagenomics analysis. bioRxiv preprint .

Giurgiu, Mădălina and Wittstruck, Nadine and Rodriguez-Fos, Elias and Chamorro González, Rocío and Brückner, Lotte and Krienelke-Szymansky, Annabell and Helmsauer, Konstantin and Hartebrodt, Anne and Koche, Richard P. and Haase, Kerstin and Reinert, Knut and Henssen, Anton G. (2023) Decoil: Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data. bioRxiv - The Preprint Server for Biology .

Nowatzky, Yannek and Benner, Philipp and Reinert, Knut and Muth, Thilo (2023) Mistle: bringing spectral library predictions to metaproteomics with an efficient search index. Bioinformatics, 39 (6). ISSN 1367-4811

Mehringer, Svenja and Seiler, Enrico and Droop, Felix and Darvish, Mitra and Rahn, René and Vingron, Martin and Reinert, Knut (2023) Hierarchical Interleaved Bloom Filter: enabling ultrafast, approximate sequence queries. Genome Biology, 24 (131). ISSN 1474-760X

Mohammadi, Somayeh and PourKarimi, Latif and Droop, Felix and De Mecquenem, Ninon and Leser, Ulf and Reinert, Knut (2023) A mathematical programming approach for resource allocation of data analysis workflows on heterogeneous clusters. The Journal of Supercomputing, 79 (17). pp. 19019-19048. ISSN 0920-8542

Pan, Chenxu and Rahn, René and Heller, David and Reinert, Knut (2023) Linear: a framework to enable existing software to resolve structural variants in long reads with flexible and efficient alignment-free statistical models. Briefings in Bioinformatics, 24 (2). ISSN 1467-5463; Online ISSN 1477-4054

Wang, Yuwei and Lian, Bin and Zhang, Haohui and Zhong, Yuanke and He, Jie and Wu, Fashuai and Reinert, Knut and Shang, Xuequn and Yang, Hui and Hu, Jialu and Mathelier, Anthony (2023) A multi-view latent variable model reveals cellular heterogeneity in complex tissues for paired multimodal single-cell data. Bioinformatics, 39 (1). ISSN 1367-4803

2022

Darvish, Mitra and Seiler, Enrico and Mehringer, Svenja and Rahn, René and Reinert, Knut and Ponty, Yann (2022) Needle: a fast and space-efficient prefilter for estimating the quantification of very large collections of expression experiments. Bioinformatics, 38 (17). pp. 4100-4108. ISSN 1367-4803

Knaust, Marius and Seiler, Enrico and Reinert, Knut and Steinke, Thomas (2022) Co-Design for Energy Efficient and Fast Genomic Search: Interleaved Bloom Filter on FPGA. In: The 2022 ACM/SIGDA International Symposium on Field-Programmable Gate Arrays (FPGA '22), 27 February - 1 March 2022, virtual.

Winkler, Jörg and Urgese, Gianvito and Ficarra, Elisa and Reinert, Knut (2022) LaRA 2: parallel and vectorized program for sequence–structure alignment of RNA sequences. BMC Bioinformatics, 23 (1). ISSN 1471-2105

2021

Neubert, Kerstin and Zuchantke, Eric and Leidenfrost, Robert Maximilian and Wünschiers, Röbbe and Grützke, Josephine and Malorny, Burkhard and Brendebach, Holger and Al Dahouk, Sascha and Homeier, Timo and Hotzel, Helmut and Reinert, Knut and Tomaso, Herbert and Busch, Anne (2021) Testing assembly strategies of Francisella tularensis genomes to infer an evolutionary conservation analysis of genomic structures. BMC Genomics, 22 (1). p. 822. ISSN 1471-2164

Leser, Ulf and Hilbrich, Marcus and Draxl, Claudia and Eisert, Peter and Grunske, Lars and Hostert, Patrick and Kainmüller, Dagmar and Kao, Odej and Kehr, Birte and Kehrer, Timo and Koch, Christoph and Markl, Volker and Meyerhenke, Henning and Rabl, Tilmann and Reinefeld, Alexander and Reinert, Knut and Ritter, Kerstin and Scheuermann, Björn and Schintke, Florian and Schweikardt, Nicole and Weidlich, Matthias (2021) The Collaborative Research Center FONDA. Datenbank-Spektrum, 21 (3). pp. 255-260. ISSN 1618-2162

Hetzel, Sara and Giesselmann, Pay and Reinert, Knut and Meissner, Alexander and Kretzmer, Helene and Alkan, Can (2021) RLM: fast and simplified extraction of read-level methylation metrics from bisulfite sequencing data. Bioinformatics, 37 (21). pp. 3934-3935. ISSN 1367-4803

Hoffmann, Marie and Monaghan, Michael T. and Reinert, Knut (2021) PriSeT: Efficient De Novo Primer Discovery. Proceedings of the 12th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics . pp. 1-12.

Seiler, Enrico and Mehringer, Svenja and Darvish, Mitra and Turc, Etienne and Reinert, Knut (2021) Raptor: A fast and space-efficient pre-filter for querying very large collections of nucleotide sequences. iScience, 24 (7). p. 102782. ISSN 25890042

Keshavan, Sandeep and Andón, Fernando Torres and Gallud, Audrey and Chen, Wei and Reinert, Knut and Tran, Lang and Fadeel, Bengt (2021) Profiling of Sub-Lethal in Vitro Effects of Multi-Walled Carbon Nanotubes Reveals Changes in Chemokines and Chemokine Receptors. Nanomaterials, 11 (4). p. 883. ISSN 2079-4991

Wolf, Silver A and Epping, Lennard and Andreotti, Sandro and Reinert, Knut and Semmler, Torsten and Birol, Inanc (2021) SCORE: Smart Consensus Of RNA Expression—a consensus tool for detecting differentially expressed genes in bacteria. Bioinformatics, 37 (3). pp. 426-428. ISSN 1367-4803

2020

Hufsky, Franziska and Lamkiewicz, Kevin and Almeida, Alexandre and Aouacheria, Abdel and Arighi, Cecilia and Bateman, Alex and Baumbach, Jan and Beerenwinkel, Niko and Brandt, Christian and Cacciabue, Marco and Chuguransky, Sara and Drechsel, Oliver and Finn, Robert D and Fritz, Adrian and Fuchs, Stephan and Hattab, Georges and Hauschild, Anne-Christin and Heider, Dominik and Hoffmann, Marie and Hölzer, Martin and Hoops, Stefan and Kaderali, Lars and Kalvari, Ioanna and von Kleist, Max and Kmiecinski, Renó and Kühnert, Denise and Lasso, Gorka and Libin, Pieter and List, Markus and Löchel, Hannah F and Martin, Maria J and Martin, Roman and Matschinske, Julian and McHardy, Alice C and Mendes, Pedro and Mistry, Jaina and Navratil, Vincent and Nawrocki, Eric P and O’Toole, Áine Niamh and Ontiveros-Palacios, Nancy and Petrov, Anton I and Rangel-Pineros, Guillermo and Redaschi, Nicole and Reimering, Susanne and Reinert, Knut and Reyes, Alejandro and Richardson, Lorna and Robertson, David L and Sadegh, Sepideh and Singer, Joshua B and Theys, Kristof and Upton, Chris and Welzel, Marius and Williams, Lowri and Marz, Manja (2020) Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research. Briefings in Bioinformatics, 22 (2). pp. 642-663. ISSN 1467-5463

Pieper, Robert and Dadi, Temesgen H. and Pieper, Laura and Vahjen, Wilfried and Franke, André and Reinert, Knut and Zentek, Jürgen (2020) Concentration and chemical form of dietary zinc shape the porcine colon microbiome, its functional capacity and antibiotic resistance gene repertoire. The ISME Journal, 14 (11). pp. 2783-2793. ISSN 1751-7362

Renard, Bernhard Y and Reinert, Knut and Seiler, Enrico and Dadi, Temesgen H and Piro, Vitor C (2020) ganon: precise metagenomics classification against large and up-to-date sets of reference sequences. Bioinformatics, 36 (Supple). i12-i20. ISSN 1367-4803

Schiefer, Christopher and Bux, Marc and Brandt, Joergen and Messerschmidt, Clemens and Reinert, Knut and Beule, Dieter and Leser, Ulf (2020) Portability of Scientific Workflows in NGS Data Analysis: A Case Study. Other. arXiv.org. (Submitted)

Schönhuth, Alexander and Moeinzadeh, M-Hossein and Yang, Jun and Muzychenko, Evgeny and Gallone, Giuseppe and Heller, David and Reinert, Knut and Haas, Stefan and Vingron, Martin (2020) Ranbow: A fast and accurate method for polyploid haplotype reconstruction. PLOS Computational Biology, 16 (5). e1007843. ISSN 1553-7358

Witt, Natalie and Andreotti, Sandro and Busch, Anne and Neubert, Kerstin and Reinert, Knut and Tomaso, Herbert and Meierhofer, David (2020) Rapid and Culture Free Identification of Francisella in Hare Carcasses by High-Resolution Tandem Mass Spectrometry Proteotyping. Frontiers in Microbiology, 11 . ISSN 1664-302X

Reinert, Knut and Iliopoulos, Costas S and Alzamel, Mai and Pockrandt, Christopher and Xu, Jinbo (2020) GenMap: ultra-fast computation of genome mappability. Bioinformatics, 36 (12). pp. 3687-3692. ISSN 1367-4803

Pfeuffer, Julianus and Sachsenberg, Timo and Dijkstra, Tjeerd M. H. and Serang, Oliver and Reinert, Knut and Kohlbacher, Oliver (2020) EPIFANY: A Method for Efficient High-Confidence Protein Inference. Journal of Proteome Research, 19 (3). pp. 1060-1072. ISSN 1535-3893

2019

Wilson, Laurence O. W. and Hetzel, Sara and Pockrandt, Christopher and Reinert, Knut and Bauer, Denis C. (2019) VARSCOT: variant-aware detection and scoring enables sensitive and personalized off-target detection for CRISPR-Cas9. BMC Biotechnology, 19 (1). ISSN 1472-6750

2018

Rahn, René and Budach, Stefan and Costanza, Pascal and Ehrhardt, Marcel and Hancox, Jonny and Reinert, Knut (2018) Generic accelerated sequence alignment in SeqAn using vectorization and multi-threading. Bioinformatics, 34 (20). pp. 3437-3445. ISSN 1367-4803

Dadi, Temesgen Hailemariam and Siragusa, Enrico and Piro, Vitor C and Andrusch, Andreas and Seiler, Enrico and Renard, Bernhard Y and Reinert, Knut (2018) DREAM-Yara: an exact read mapper for very large databases with short update time. Bioinformatics, 34 (17). i766-i772. ISSN 1367-4803

Grześkowiak, Łukasz and Martínez-Vallespín, Beatriz and Dadi, Temesgen H and Radloff, Judith and Amasheh, Salah and Heinsen, Femke-Anouska and Franke, Andre and Reinert, Knut and Vahjen, Wilfried and Zentek, Jürgen and Pieper, Robert (2018) Formula Feeding Predisposes Neonatal Piglets to Clostridium difficile Gut Infection. The Journal of Infectious Diseases, 217 (9). pp. 1442-1452. ISSN 0022-1899

Kianfar, Kiavash and Pockrandt, Christopher and Torkamandi, Bahman and Luo, Haochen and Reinert, Knut (2018) Optimum Search Schemes for Approximate String Matching Using Bidirectional FM-Index. bioRxiv, The Preprint Server for Biology .

2017

Pfeuffer, Julianus and Sachsenberg, Timo and Alka, Oliver and Walzer, Mathias and Fillbrunn, Alexander and Nilse, Lars and Schilling, Oliver and Reinert, Knut and Kohlbacher, Oliver (2017) OpenMS – A platform for reproducible analysis of mass spectrometry data. Journal of Biotechnology, 261 . pp. 142-148. ISSN 01681656

Reinert, Knut and Dadi, Temesgen Hailemariam and Ehrhardt, Marcel and Hauswedell, Hannes and Mehringer, Svenja and Rahn, René and Kim, Jongkyu and Pockrandt, Christopher and Winkler, Jörg and Siragusa, Enrico and Urgese, Gianvito and Weese, David (2017) The SeqAn C++ template library for efficient sequence analysis: A resource for programmers. Journal of Biotechnology, 261 . pp. 157-168. ISSN 01681656

Roehr, Johannes T. and Dieterich, Christoph and Reinert, Knut (2017) Flexbar 3.0 – SIMD and multicore parallelization. Bioinformatics, 33 (18). pp. 2941-2942. ISSN 1367-4803

Schwartz, Russell and Reinert, Knut, eds. (2017) 17th International Workshop on Algorithms in Bioinformatics (WABI 2017). LIPICS, 88 . Dagstuhl LIPIcs, Saarbrücken/Wadern. ISBN 978-3-95977-050-7

Kim, Jongkyu and Reinert, Knut (2017) Vaquita: Fast and Accurate Identification of Structural Variation Using Combined Evidence. In: 17th International Workshop on Algorithms in Bioinformatics (WABI 2017). LIPICS (88). Dagstuhl LIPIcs, Saarbrücken/Wadern, 185(13:1)-198(13:14). ISBN 978-3-95977-050-7

Pockrandt, Christopher and Ehrhardt, Marcel and Reinert, Knut (2017) EPR-Dictionaries: A Practical and Fast Data Structure for Constant Time Searches in Unidirectional and Bidirectional FM Indices. In: Research in Computational Molecular Biology. RECOMB 2017. Lecture Notes in Computer Science (LNCS), 10229 . Springer, Cham, pp. 190-206. ISBN 978-3-319-56970-3 (elektronisch)

Dadi, Temesgen Hailemariam and Renard, Bernhard Y. and Wieler, Lothar H. and Semmler, Torsten and Reinert, Knut (2017) SLIMM: species level identification of microorganisms from metagenomes. PeerJ, 5 . e3138. ISSN 2167-8359

Audain, Enrique and Uszkoreit, Julian and Sachsenberg, Timo and Pfeuffer, Julianus and Liang, Xiao and Hermjakob, Henning and Sanchez, Aniel and Eisenacher, Martin and Reinert, Knut and Tabb, David L. and Kohlbacher, Oliver and Perez-Riverol, Yasset (2017) In-depth analysis of protein inference algorithms using multiple search engines and well-defined metrics. Journal of Proteomics, 150 . pp. 170-182. ISSN 18743919

Meyers, Gene and Pop, Mihai and Reinert, Knut and Warnow, Tandy (2017) Dagstuhl Reports, Vol. 6, No. 8, pp. 91-130: Next Generation Sequencing (Dagstuhl Seminar 16351). Documentation. Schloss Dagstuhl--Leibniz-Zentrum fuer Informatik, Dagstuhl, Germany.

2016

Jäger, Marten and Schubach, Max and Zemojtel, Tomasz and Reinert, Knut and Church, Deanna M. and Robinson, Peter N. (2016) Alternate-locus aware variant calling in whole genome sequencing. Genome Medicine, 8 (1). ISSN 1756-994X

Zühlke, Martin and Riebe, Daniel and Beitz, Toralf and Löhmannsröben, Hans-Gerd and Andreotti, Sandro and Reinert, Knut and Zenichowski, Karl and Diener, Marc (2016) High-performance liquid chromatography with electrospray ionization ion mobility spectrometry: Characterization, data management, and applications. Journal of Separation Science, 39 (24). pp. 4756-4764. ISSN 16159306

Röst, Hannes L and Sachsenberg, Timo and Aiche, Stephan and Bielow, Chris and Weisser, Hendrik and Aicheler, Fabian and Andreotti, Sandro and Ehrlich, Hans-Christian and Gutenbrunner, Petra and Kenar, Erhan and Liang, Xiao and Nahnsen, Sven and Nilse, Lars and Pfeuffer, Julianus and Rosenberger, George and Rurik, Marc and Schmitt, Uwe and Veit, Johannes and Walzer, Mathias and Wojnar, David and Wolski, Witold E and Schilling, Oliver and Choudhary, Jyoti S and Malmström, Lars and Aebersold, Ruedi and Reinert, Knut and Kohlbacher, Oliver (2016) OpenMS: a flexible open-source software platform for mass spectrometry data analysis. Nature Methods, 13 (9). pp. 741-748. ISSN 1548-7091

de la Garza, Luis and Veit, Johannes and Szolek, Andras and Röttig, Marc and Aiche, Stephan and Gesing, Sandra and Reinert, Knut and Kohlbacher, Oliver (2016) From the desktop to the grid: scalable bioinformatics via workflow conversion. BMC Bioinformatics, 17 (1). ISSN 1471-2105