Repository: Freie Universität Berlin, Math Department

Mason – A Read Simulator for Second Generation Sequencing Data

Holtgrewe, M. (2010) Mason – A Read Simulator for Second Generation Sequencing Data. Technical Report FU Berlin .

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We present a read simulator software for Illumina, 454 and Sanger reads. Its features include position specific error rates and base quality values. For Illumina reads, we give a comprehensive analysis with empirical data for the error and quality model. For the other technologies, we use models from the literature. It has been written with performance in mind and can sample reads from large genomes. The C++ source code is extensible, and freely available under the GPL/LGPL.

Item Type:Article
Subjects:Mathematical and Computer Sciences > Computer Science
Divisions:Department of Mathematics and Computer Science > Institute of Computer Science > Algorithmic Bioinformatics Group
ID Code:962
Deposited By: Dipl. Inform. Manuel Holtgrewe
Deposited On:08 Oct 2011 13:21
Last Modified:03 Mar 2017 14:40

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